Tamblyn was born in Santa Monica, California, the daughter of actor Russ Tamblyn and musician/writer Bonnie Murray. At the age ten, she played Pippi Longstocking at the Santa Monica Alternative School House; her father's agent, Sharon Debord, was attending as a family friend and ended up convincing her father to allow Tamblyn to go on auditions.

Amber as Aubrey Davis in The Grudge 2Tamblyn was cast as Emily Bowen Quartermaine on the soap opera General Hospital, a role which she played...